*UPDATE* I recommend that readers take a look at the comments following this article for important clarifications
Someone on the
Australian Vaccination Network's (
AVN) Facebook
page posted a link to an Adelaide Now story about a
hospital doctor contracting whooping cough.
In short, a doctor at a Women's and Children's hospital tested positive for whooping cough and the hospital has taken action to identify anyone who was potentially infected by him. The story does not mention any confirmed infections among the 59 people identified as having had contact during the infectious period, but says 25 were given precautionary antibiotics. The article finishes with a call for children to be fully vaccinated.
The doctor's vaccination status was not mentioned but is the cause of some speculation at AVN Central. An AVN administrator, posting only as
Australian Vaccination Network, wrote:
What was the doctor's vaccination status? How long since his last shot and if it was fairly recent, what does this say about the effectiveness of vaccination? While the unvaccinated are being blamed for the outbreak that's been going on in Oz for the last few years (despite our record-high levels of vaccination), cases like this where a health professional has contracted and possibly passed on pertussis are far from rare.
Given that we don't know the doctor's vaccination history, the comment seems somewhat pointless. This doctor might be one of those who the AVN regularly tell us about - doctors opposed to vaccination. Even if we assume the doctor was vaccinated, anyone who knows anything about vaccination knows that it isn't claimed to be 100% effective. So the doctor could be fully up to date with his or her vaccinations, and still become infected. That, in itself, isn't even news.
The next response on the Facebook thread was from Meryl Dorey, also posting as
Australian Vaccination Network but at least including an unfortunate
MD at the end of her comment
(she isn't a doctor - of any kind. She's not even a scientist. For the record, neither am I). Here's a screenshot of her comment...
Her opening remark was what caught my attention...
The other question is - was this mutation something natural or did the vaccination actually CAUSE it?
Now, I'm no biologist - I didn't even do biology in high school (
I did chemistry and physics instead) but I really don't think she has even a layperson's concept of what mutation is.
As always, I'm open to corrections but, for what it's worth, here's my layman's summary of mutation.
Organisms are never quite identical. Minor differences in DNA occur across a species. Sometimes these changes are bad for the organism and those individuals die or fail to reproduce. Sometimes the changes seem to do nothing, bad or good, for the organism but if the organism survives and reproduces, those changes can be passed on. Few changes would be likely to automatically deliver an immediate, significant benefit to an individual or species.
However, some of those seemingly insignificant changes might become beneficial for the organism if its circumstances change. In a season where grass is in short supply, those animals in a group that have longer necks might benefit by reaching leaves in trees. Shorter individuals might die that season and the "longer-neck mutation" is now part of the species. It has mutated but it didn't intentionally grow a longer neck to survive, the mutation wasn't "caused", as such. It survived because some individuals were different enough to exploit a differing situation that others couldn't. It's evolution in a nutshell.
With bacteria, like that which causes whooping cough, all that needs to happen is for the organism to change just enough to not be recognised by an immune system that has already been exposed to the original organism.
But mutation is a numbers game. It's occurring all the time in all organisms but remember, not all mutations are beneficial. Some of the mutations might make the "new" bacteria different to the old bacteria but it might also be less virulent - more easily defeated. Such mutations pose little threat to us.
Think of beneficial mutation a little like choosing winning Lotto numbers. To really improve your chances of winning Lotto, you need to try a hell of a lot of number combinations - and you still might not win.
Beneficial mutation is best served by the ability to constantly reproduce as each new generation can have different "combinations". Then we need enough individuals to carry just the right combination - and that requires still more opportunities to reproduce. Since infected people will usually either beat the infection (
possibly with long-term side effects), receive antibiotics or die, the organism needs to keep finding new hosts in order to keep playing the "mutation lottery"
A large population of unvaccinated (
or never-infected) people offers the best opportunity for the bacterium to evolve a mutant combination that allows it to by-pass a pertussis-ready immune system.
I am at an absolute loss to even contemplate how a vaccine for whooping cough could actually CAUSE such a mutation. It's not like the bacteria are weighing up the situation and choosing which parts of their DNA need to be changed in order to survive - they are just lucky enough to sometimes develop a difference that makes them look different to a pre-primed immune system. Such mutations would occur even if vaccination had never been invented.
Further down the AVN Facebook page is a question about whether live virus vaccinations are contagious.
I was just wondering - Which vaccines are live culture? When a child is being vaccinated, does the doctor tell them to stay away from other people especially babies & children for a few days, because of the risk of that child spreading the live culture that they were just vaccinated against.
The obvious short answer to this, to a layman like me, would be "no" since vaccination would be completely pointless if it posed exactly the same threat as the natural disease it is designed to contain. But this is an AVN page so you can bet that isn't the answer that's given.
The first reply is just bizarre so I'm just going to leave it well alone.
The second reply comes from Meryl Dorey, self-described leading expert on vaccination.
Hi Fiona - Live virus vaccines include the MMR (measles, mumps and rubella), Chicken Pox (Varicella) if we license the Shingles vaccine in Australia, that will also be a live virus, some of our licensed flu vaccines are live though they are... not used often here, the oral polio vaccine which is also not used often in Australia is live, rabies is live which is only used for bat handlers here in Oz and I think I'm forgetting one but it's too early in the morning...does anyone out there know if I have?
I haven't checked all the facts of Dorey's reply but I do note a significant omission which could have put the questioner's mind at ease. The live viruses used in vaccines like MMR are "attenuated". From
wikipedia (
my bolding)...
An attenuated vaccine is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live").[1] Attenuation takes a living agent and alters it so that it becomes harmless or less virulent. These vaccines contrast to those produced by "killing" the virus (inactivated vaccine).
It seems to me, and I remind you I'm neither a doctor nor a scientist, that even if the vaccinated child were contagious, then any subsequent infection would be mild. Again, I'm ready to stand corrected if I'm wrong
(*UPDATE* I recommend that readers take a look at the comments following this article for important clarifications). Even so, Dorey's answer seems sadly lacking in important details that one might expect to find from a group that claims to offer parents information that will help them make vaccination decisions.
But why are AVN members concerned by infections - either from doctors or vaccinated kids? After all, Meryl Dorey is on record as saying whooping cough isn't lethal and that it's little more than a bad cough that is easily treated with sugar and/or water (
okay, she called it "homeopathy" but that sounds far too "sciencey" for something which actually is just sugar or water). Anti-vaxxers often argue that our immune systems are strengthened by contracting infections, so surely they should welcome infectious doctors, vaccinated-pox parties and biological mutation.